Focus on Osteoporosis

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Progress in osteoporosis and fracture prevention: focus on postmenopausal women

In the past decade, we have witnessed a revolution in osteoporosis diagnosis and therapeutics. This includes enhanced understanding of basic bone biology, recognizing the severe consequences of fractures in terms of morbidity and short-term re-fracture and mortality risk and case finding based on clinical risks, bone mineral density, new imaging approaches, and contributors to secondary osteopo...

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The pathway of the receptor activator of the nuclear factor kappaB ligand (RANKL), RANK and osteoprotegerin (OPG) plays a central role in coupling bone formation and resorption during normal bone turnover and in a wide spectrum of diseases characterized by disturbed bone remodeling, increased bone resorption and bone destruction (osteoporosis, Paget's disease of bone, rheumatoid arthritis [RA],...

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Communicating about overdiagnosis: Learning from community focus groups on osteoporosis

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Osteoporosis is a multifactorial skeletal disorder characterized by decreased bone mass and deteriorated microarchitecture that lead to increased risk of fracture. The disuse osteoporosis refers to bone mass decrements under conditions of decreased mechanical loading, including decreased ground force reaction, muscular contraction, and microgravity-related bone loss in astronauts after space fl...

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Shifting the focus in fracture prevention from osteoporosis to falls.

124 BMJ | 19 January 2008 | VoluMe 336 Fractures are a rapidly growing problem among older people. Hip fractures alone cost over $20bn (£10bn; €13bn) in the United States in 1997.1 Any intervention that may reduce the risk of fracture at either the individual or population level therefore warrants critical appraisal. The mainstay of current strategies to prevent fractures is to screen for osteo...

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ژورنال

عنوان ژورنال: AAOHN Journal

سال: 2004

ISSN: 0891-0162

DOI: 10.1177/216507990405200710